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Antigenic Specificity | CAF1A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CAF1A antibody detects endogenous levels of total CAF1A. Function: Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci (By similarity).Subunit Structure: Homodimer. P |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus. DNA replication foci. Tissue Specificity: Active complex is found in G1, S and G2 phases. Predicted Cross Reactivity: Bovine, Sheep, Dog Similarity: Bovine (100%), Sheep (100%), Dog (100%) |
Other Names | [CAF 1; CAF 1 subunit A; CAF; CAF I 150 kDa subunit; CAF I p150; CAF-1 subunit A; CAF-I 150 kDa subunit; CAF-I p150; CAF1; CAF1A_HUMAN; CAF1B; CAF1P150; CHAF1A; Chromatin assembly factor 1 subunit A; Chromatin Assembly Factor 1 Subunit A p150; Chromatin assembly factor I (150 kDa); Chromatin assembly factor I 150 kDa; Chromatin assembly factor I p150 subunit; DCAF1; hp150; MGC71229; P150] |
Gene, Accession # | [CAF1A], Gene ID: 10036, NCBI: NP_005474.2, UniProt: Q13111 |
Catalog # | MBS9604716 |
Price | $240, $280 |
Order / More Info | CAF1A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |