SIX1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | SIX1 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Homeobox protein SIX1(SIX1) detection. Tested with WB in Human. Background: Homeobox protein SIX1 (Sineoculis homeobox homolog 1) is a protein that in humans is encoded by the SIX1 gene. It is mapped to 14q23.1. The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in limb development. Defects in this gene are a cause of autosomal dominant deafness type 23 (DFNA23) and branchiootic syndrome type 3 (BOS3). |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SIX1 (245-282aa NYSLPGLTASQPSHGLQTHQHQLQDSLLGPLTSSLVDL), different from the related mouse sequence by one amino acid. Ig Type: Rabbit IgG |
| Other Names | [Homeobox protein SIX1; BOS3; DFNA23; Homeobox protein SIX1; OTTHUMP00000179042; Sine oculis homeobox homolog 1; SIX homeobox 1; SIX1; SIX1_HUMAN; TIP39; SIX homeobox 1], [SIX1; SIX1; BOS3; TIP39; DFNA23] |
| Gene, Accession # | [SIX1], Gene ID: 6495, NCBI: NP_005973.1, UniProt: Q15475 |
| Catalog # | MBS177809 |
| Price | $280 |
| Order / More Info | SIX1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Entrez Gene: SIX1 sine oculis homeobox homolog 1 (Drosophila). 2. Boucher CA, Carey N, Edwards YH, Siciliano MJ, Johnson KJ (Apr 1996). Cloning of the human SIX1 gene and its assignment to chromosome 14. Genomics 33 (1): 140-2. 3. Ruf RG, Xu PX, Silvius D, Otto EA, Beekmann F, Muerb UT, Kumar S, Neuhaus TJ, Kemper MJ, Raymond RM, Brophy PD, Berkman J, Gattas M, Hyland V, Ruf EM, Schwartz C, Chang EH, Smith RJ, Stratakis CA, Weil D, Petit C, Hildebrandt F (May 2004). SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1-SIX1-DNA complexes. Proceedings of the National Academy of Sciences of the United States of America 101 (21): 8090-5. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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