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Antigenic Specificity | HSP27 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Human HSP27, mouse HSP25 and alpha/beta crystallin are part of a diverse family of small heat shock proteins which are produced in all organisms. They function as chaperone like proteins by binding unfolded polypeptides and preventing uncontrolled protein aggregation. HSP27 is believed to exist mainly as oligomers of as many as 8 40 HSP27 protein monomers in cells and data suggests that the large oligomers of HSP27 have a chaperone like activity by serving as a site where unfolding proteins may bind until ATP and HSP70 dependent refolding can occur. HSP27 is believed to protect cells by enhancing cellular glutathione levels and elevated glutathione levels have been measured in cells overexpressing HSP27. Data from studies using wild type HS |
Immunogen | Immunogen: HSP27 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human HSP27, different from the related Rabbit sequence by two amino acids, as the immunogen |
Other Names | [Affinity Purified Rabbit HSP27; HSP27; HSP27; HSP 27; HSP-27; HSPB2; HSP-27; HSP-27; Heat Shock 27Kda Protein 2; Hs.78846; HSP27; HSP27; MGC133245; LOH11CR1K; HSP 27; MKBP] |
Gene, Accession # | [HSP27] |
Catalog # | MBS5312598 |
Price | $345 |
Order / More Info | HSP27 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |