Edit |   |
Antigenic Specificity | RACK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to Human RACK1. The highly conserved receptor for activated C kinase 1 (RACK1), homologous to the beta subunit of heterotrimeric G-proteins, was originally identified through its binding of active PKCbetaII and other classical PKC isoforms (1). RACK1 is a scaffold protein that recruits PKC and a wide range of other proteins to specific subcellular locations, promoting the formation of multiprotein complexes to induce and integrate various signaling pathways (reviewed in 2). One example of this is its enhancement of PKC-dependent JNK activation (3). RACK1 protein also resides in the eukaryotic ribosome, suggesting the possibility that RACK1 participates in the assembly of signaling complexes that regulate translation as wel |
Immunogen | Immunogen: A synthetic -peptide of human RACK1 |
Other Names | [GNB2L1; GNB2L1; Gnb2-rs1; H12.3; HLC-7; PIG21; RACK1], [GNB2L1; GNB2L1; H12.3; HLC-7; PIG21; RACK1; Gnb2-rs1; HLC-7; RACK1] |
Gene, Accession # | Gene ID: 10399, NCBI: NP_006089.1, UniProt: P63244 |
Catalog # | MBS125911 |
Price | $200, $275, $430 |
Order / More Info | RACK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Ron, D. et al. (1994) Proc. Natl. Acad. Sci. USA 91, 839-843. 2. Lopez-Bergami, P. et al. (2005) Mol. Cell 19, 309-320. 3. McCahill, A. et al. (2002) Mol. Pharmacol. 62, 1261-1273. 4. Nilsson, J. et al. (2004) EMBO Rep. 5, 1137-1141. 5. Chang, B. Y. et al. (2002) Oncogene 21, 7619-7629. |