beta-Catenin Antibody from MYBIOSOURCE INC.

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Antigenic Specificitybeta-Catenin
Clonepolyclonal
Host Speciesn/a
Reactive Speciesmouse, rat, human
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of N-terminal residues of beta-Catenin. beta-Catenin is a multifunctional adaptor protein involved in cadherin-mediated cell-cell adhesion and in responding to the activation of several signal transduction pathways. CK1 phosphorylates beta-catenin on Ser45. This phosphorylation event primes beta-catenin for subsequent phosphorylation by GSK-3. GSK-3beta destabilizes beta-catenin by phosphorylating it at Ser33, Ser37 and Thr41.). Mutations in beta-Catenin have been implicated in its accumulation and various forms of carcinomas.
Immunogenn/a
Other Names[catenin beta-1; Catenin beta-1; catenin beta-1; catenin (cadherin associated protein), beta 1; Beta-catenin], [Ctnnb1; Ctnnb1; Bfc; Mesc; Catnb; Catnb]
Gene, Accession #Gene ID: 12387, NCBI: NP_001159374.1, UniProt: Q02248
Catalog #MBS857332
Price$280
Order / More Infobeta-Catenin Antibody from MYBIOSOURCE INC.
Product Specific References1. Kikuchi A.; Regulation of beta-catenin signaling in the Wnt pathway.; Biochem. Biophys. Res. Commun. 2.8:2.3.2.8(2.00). Dobrosotskaya I.Y., James G.L.; MAGI-1.interacts with beta-catenin and is associated with cell-cell adhesion structures.; Biochem. Biophys. Res. Commun. 2.0:903.909(2.00).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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