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Antigenic Specificity | ECE2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total ECE2 protein. Endothelin-converting enzymes, such as ECE2 (EC 3.4.24.71), are type II metalloproteases that generate functionally pleiotropic members of the endothelin vasoactive peptide family. It converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity. |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to a region derived from internal residues of human endothelin converting enzyme 2 |
Other Names | [endothelin converting enzyme 2; Methyltransferase-like region] |
Gene, Accession # | [ECE2], Gene ID: 9718, NCBI: NP_001032401.1, UniProt: O60344 |
Catalog # | MBS9404822 |
Price | $255 |
Order / More Info | ECE2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |