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Antigenic Specificity | sod2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: sod2 antibody detects endogenous levels of total sod2. Function: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.Subunit Structure: Homotetramer.Post-translational Modifications: Nitrated under oxidative stress. Nitration coupled with oxidation inhibits the catalytic activity. Acetylation at Lys-122 decreases enzymatic activity. Deacetylated by SIRT3 upon exposure to ionizing radiations or after long fasting (By similarity). Polyubiquitinated; leading to proteasomal degradation. Deubiquitinated by USP36 which increases protein stability.Similarity: Belongs to the iron/manganese superoxide dismutase family. |
Immunogen | Immunogen: A synthesized peptide derived from human sod2 Subcellular Location: Mitochondrion Matrix. Tissue Specificity: Expression is regulated by KRIT1. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Xenopus Similarity: Pig (100%), Zebrafish (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Xenopus (100%) |
Other Names | [Indophenoloxidase B; IPO B; IPOB; Manganese containing superoxide dismutase; Manganese SOD; Manganese superoxide dismutase; Mangano superoxide dismutase; Mn SOD; Mn superoxide dismutase; MNSOD; MVCD6; SOD 2; SOD2; SODM_HUMAN; Superoxide dismutase [Mn] mitochondrial; Superoxide dismutase [Mn], mitochondrial; Superoxide dismutase 2 mitochondrial] |
Gene, Accession # | [sod2], Gene ID: 6648, NCBI: NP_000627.2, UniProt: P04179 |
Catalog # | MBS9601317 |
Price | $240, $280 |
Order / More Info | sod2 Antibody from MYBIOSOURCE INC. |
Product Specific References | Qiu H, Ma J, Wu H, Ding C; Journal: Naunyn Schmiedebergs Arch Pharmacol. DL-3-n-butylphthalide improves ventricular function, and prevents ventricular remodeling and arrhythmias in post-MI rats. Wu M, Gu J, Mei S, Xu D, Jing Y, Yao Q, Chen M, Yang M, Chen S, Yang B, Qi N, Hu H, Wuthrich RP, Mei C; Journal: Nephrol Dial Transplant. Resveratrol delays polycystic kidney disease progression through attenuation of nuclear factor kB-induced inflammation. Sun H, Xu S, Yi L, Chen Y, Wu P, Cao Z, Zhou L, Jiang Y, Zhang D; Journal: Neurogastroenterol Motil. Role of 5-HT1A receptor in insular cortex mediating stress-induced visceral sensory dysfunction. |