VEGF-R2/CD309/Flk-1/KDR3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | VEGF-R2/CD309/Flk-1/KDR3 |
| Clone | [DC101] |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG1, kappa |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Western Blot (WB), Blocks Binding of VEGF to VEGF-R2, Inhibits VEGF-induced Signaling, Blocks Tumor Growth in mice, Neutralizing |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This MAb is specific to Mouse VEGFR2/FLK-1/CD309 and does not cross-react with FLK-2. VEGFR2 is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Endothelial cells, embryonic tissues, and megakaryocytes mainly express VEGFR2. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGFR2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGFR2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration. |
| Immunogen | Immunogen: Recombinant full-length Mouse VEGFR2 protein |
| Other Names | [CD309; Fetal liver kinase 1 (FLK-1); KDR; Kinase insert domain receptor (a type III receptor tyrosine kinase); KRD1; Ly73; Protein tyrosine kinase receptor FLK1; Vascular endothelial growth factor receptor 2] |
| Gene, Accession # | [KDR], Gene ID: 16542 |
| Catalog # | MBS4381455 |
| Price | $190, $340, $340 |
| Order / More Info | VEGF-R2/CD309/Flk-1/KDR3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Witte L, et al. Cancer Metastasis Rev. 1998 Jun;17(2):155-61. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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