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Antigenic Specificity | Beclin 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.2 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Beclin is a Bcl-2 binding protein. Its structure includes a Bcl-2 binding coiled-coil region, and a leucine-rich nuclear export signal (NES). Beclin protein colocalizes with intracytoplasmic organelles and nuclei in normal COS7 and MCF7 cells. Beclin interaction with Bcl-2 may be involved with host viral defense, since over expression of beclin inhibits Sindbis virus replication and expression of beclin lacking the Bcl-2 binding domain has no antiviral effects. |
Immunogen | Immunogen: Synthetic peptide corresponding to residues around amino acid 25 of mouse Beclin 1 |
Other Names | [BECN1; GT197; Beclin-1; beclin1; ATG6; VPS30], [Becn1; Becn1; Atg6; 4921513J16Rik; 5430417M23Rik] |
Gene, Accession # | Gene ID: 56208, NCBI: NP_062530.2, UniProt: O88597 |
Catalog # | MBS840715 |
Price | $150, $290 |
Order / More Info | Beclin 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |