Puma Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Puma antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Puma |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | IgG |
| Format | unconjugated |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The p53 upregulated modulator of apoptosis (PUMA) also known as Bcl-2-binding component 3 (BBC3), is a pro-apoptotic protein, member of the Bcl-2 protein family. In humans, the Bcl-2-binding component 3 protein is encoded by the BBC3 gene. The expression of PUMA is regulated by the tumor suppressor p53. PUMA is involved in p53-dependent and -independent apoptosis induced by a variety of signals, and is regulated by transcription factors, not by post-translational modifications. After activation, PUMA interacts with antiapoptotic Bcl-2 family members, thus freeing Bax and/or Bak which are then able to signal apoptosis to the mitochondria. |
| Immunogen | Source Note: This monoclonal antibody is produced by immunizing animals with a polypeptide corresponding to Puma protein. |
| Other Names | [JFY-1; p53 up-regulated modulator of apoptosis; PUMA; Bcl-2-binding component 3], [BBC3; BBC3; JFY1; PUMA; JFY-1; PUMA] |
| Gene, Accession # | [Puma], Gene ID: 27113, NCBI: NP_001120712.1, UniProt: Q9BXH1 |
| Catalog # | MBS435293 |
| Price | $350, $565 |
| Order / More Info | Puma Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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