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Antigenic Specificity | Talin 1/TLN1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for Talin 1 detection. Tested with WB, IHC-P in Human; Mouse; Rat.Background: Talin-1 is a protein that in humans is encoded by the TLN1 gene. This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains e |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence of human Talin 1 (QQLAPREGISQEALHTQMLTAVQEISHLIEPLANAARAEASQ). |
Other Names | [Talin-1; TLN1; KIAA1027; TLN; Talin 1] |
Gene, Accession # | [TLN1], Gene ID: 7094, NCBI: NP_006280.3, UniProt: Q9Y490 |
Catalog # | MBS1751438 |
Price | $315 |
Order / More Info | Talin 1/TLN1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Ben-Yosef T, Francomano CA (Dec 1999). Characterization of the human talin (TLN) gene: genomic structure, chromosomal localization, and expression pattern. Genomics. 62 (2): 316-9. 2. Gilmore AP, Ohanian V, Spurr NK, Critchley DR (Aug 1995). Localisation of the human gene encoding the cytoskeletal protein talin to chromosome 9p. Human Genetics. 96 (2): 221-4. |