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Antigenic Specificity | CD40L |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for CD40 ligand(CD40LG) detection. Tested with WB, IHC-P in Human. Background: CD40 ligand(CD40L) is a type II membrane protein of 261 amino acids on activated T cells that induces B cell proliferation and immunoglobulin secretion. It has homology with tumour necrosis factor-alpha and -beta, and has important functions in B-cell activation and differentiation. Human CD40L with 5 exons, is mapped to the proximal region of the mouse X chromosome on Xq26.3-27.1, and can be detected on T cells but is absent from B cells and monocytes. Since CD40L is expressed on platelets and released from them on activation, its predictive value as a marker for clinical outcome and the therapeutic effect of inhibitio |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human CD40L (47-65aa HRRLDKIEDERNLHEDFVF), different from the related mouse sequence by three amino acids, rat sequence by four amino acids. |
Other Names | [CD40 ligand(CD40-L); CD40 ligand; CD 154; CD 40L; CD154; CD154 antigen; CD40 antigen ligand; CD40 homologue; CD40 L; CD40 ligand; CD40 ligand, soluble form; CD40-L; CD40L_HUMAN; CD40LG; gp39; hCD40L; HIGM1; Hyper IgM syndrome; IGM; IMD3; Ly62; T B cell activating molecule; T BAM; T cell antigen GP39; T-cell antigen Gp39; TBAM; TNF related activation protein; TNF superfamily member 5; TNF-related activation protein; Tnfsf5; TRAP; Tumor Necrosis Factor(ligand) Superfamily Member 5; Tumor necrosis factor ligand superfamily member 5], [CD40LG; CD40LG; IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L; CD40L; TNFSF5; TRAP; CD40-L; TRAP] |
Gene, Accession # | [CD40LG], Gene ID: 959, NCBI: P29965.1, UniProt: P29965 |
Catalog # | MBS175368 |
Price | $315 |
Order / More Info | CD40L Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |