SCF Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SCF |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | SCF Antibody: Stem cell factor (SCF) is the ligand of the c-Kit oncogene and is expressed by various structural and inflammatory cells in the airways. Binding of SCF by the c-Kit receptor leads to homodimerization of the receptor and the activation of signalling pathways such as PI-3, PLC-gamma, Jak/STAT, and MAP kinase pathways. SCF expression leads to the induction of mast cell survival and the expression and release of histamine, pro-inflammatory cytokines and chemokines. The inhibition of the SCF/c-Kit pathway leads to a decrease in histamine levels, mast cell and eosinophil infiltration, IL-4 production and airway hyperresponsiveness, suggesting this pathway may be a useful therapeutic target in inflammatory diseases such as asthma. At |
| Immunogen | Immunogen: SCF antibody was raised against an 18 amino acid synthetic peptide from near the center of human SCF. Buffer: SCF Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [SCF; SF; MGF; SCF; FPH2; KL-1; Kitl; SHEP7; Kit ligand; Mast cell growth factor; KIT ligand], [KITLG; KITLG; SF; MGF; SCF; FPH2; KL-1; Kitl; SHEP7; MGF; SCF; MGF; SCF; sKITLG] |
| Gene, Accession # | [KITLG], Gene ID: 4254, NCBI: P21583.1, UniProt: P21583 |
| Catalog # | MBS151230 |
| Price | $375 |
| Order / More Info | SCF Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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