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Antigenic Specificity | Tyro3 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Tyro3 antibody detects endogenous levels of total Tyro3. Description: Tyro3 (also known as Sky and Rse), with 890-amino acid protein (about 98kDa), belongs to the Axl/Tyro3 family of receptor tyrosine kinases, which also includes Axl and Mer.Gas6 (growth arrest-specific gene-6) is a ligand for all members of the Axl family and they play essential roles in spermatogenesis, immunoregulation, and phagocytosis.Tyro3 was expressed at high levels during postnatal development and in the adult in the cortex.Tyro3 and Gas6 have neurotrophic roles in the nervous system.In addition, the signalling interactions of Axl and Tyro3 may play roles in tumourigenesis, inflammation as well as other cell proliferative diseases.Function: Recepto |
Immunogen | Immunogen: Purified recombinant fragment of human Tyro3 expressed in E. Coli Subcellular Location: Cell Membrane Tissue Specificity: Abundant in the brain and lower levels in other tissues. |
Other Names | [Brt; BYK; DTK; Etk-2; protein tyrosine kinase 3; Rek; RSE; SKY; Tif; tyro3; TYRO3 protein tyrosine kinase; TYRO3_HUMAN; Tyrosine-protein kinase byk; Tyrosine-protein kinase DTK; Tyrosine-protein kinase receptor TYRO3; Tyrosine-protein kinase RSE; Tyrosine-protein kinase SKY; Tyrosine-protein kinase TIF] |
Gene, Accession # | [Tyro3], Gene ID: 7301, NCBI: NP_001317193.1, UniProt: Q06418 |
Catalog # | MBS9602534 |
Price | $235, $295, $370 |
Order / More Info | Tyro3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |