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Antigenic Specificity | Pan-Cytokeratin, 2 Clones (AE1/AE3) |
Clone | AE1/AE3 |
Host Species | Mouse |
Reactive Species | human, chicken, Cattle, rabbit, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 5 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Formalin/Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Pan-Cytokeratin (AE1/AE3) contains two different clones, which label the majority of normal epithelia and carcinoma. Cytokeratins are a group of water soluble filament proteins, which are components of the cytoskeleton of the epidermis and other epithelial cells. Gelelectrophoretic investigation revealed 20 different Cytokeratins, characterised by different molecular sizes and pI-values. They can be subdivided into basic and acid subfamilies. The nomenclature according to Moll et al. (1982) is most commonly used. Basic cytokeratins (52-67 kD) and acid cytokeratins (40, 48, 50, 50', 56,5 kD) CK 1-8, 10, 14-16 and 19 according to the nomenclature by Moll (1982). |
Immunogen | Immunogen: Human epithelial keratins |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS397089 |
Price | $280 |
Order / More Info | Pan-Cytokeratin, 2 Clones (AE1/AE3) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Moll R., Franke W.W., Schiller D.L., Geiger B., and Krepler R. (1982) The Catalog of Human Cytokeratins: Patterns of Expression in Normal Epithelia, Tumors and Cultured Cells. Cell 31; 11 ff. 2. Sun T.-T. Tseng S.C.G., Huang A.J.W., Cooper D., Lynch M.H., Weiss R., Eichner R., and Schermer (1985) Monoclonal antibody studies of keratin expression: A review. In: Intermediate Filaments, Wang E. et al. eds. N.Y. Acad. Sci. 455, pp 307 ff. |