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Antigenic Specificity | PRKCI |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefo |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [PKCzeta/lambda: DXS1179E; MGC26534; PKCI; nPKC-iota], [PRKCI; PRKCI; PKCI; DXS1179E; nPKC-iota; DXS1179E; PRKC-lambda/iota; aPKC-lambda/iota] |
Gene, Accession # | [PRKCI], Gene ID: 5584, NCBI: P41743.2, UniProt: P41743 |
Catalog # | MBS125450 |
Price | $275, $430 |
Order / More Info | PRKCI Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |