KRT17 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKRT17
Clone[AT9F3]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a, k
FormatProtein A purified
Size0.05 mL, 0.1 mL
Concentration1 mg/ml
ApplicationsELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionKeratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments. Keratin 17 is involved in wound healing and cell growth, two processes that require rapid cytoskeletal remodeling. Keratinocytes deficient in keratin 17 exhibit abnormal Akt/mTOR signaling and fail to produce an increase in translation, cell size, or growth; these cells also exhibit abnormal 14-3-3 sigma localization.
ImmunogenImmunogen: Recombinant human KRT17 (1-432aa) purified from E. coli
Other Names[Keratin type I cytoskeletal 17; Keratin; type I cytoskeletal 17; K17; PC; PC2; PCHC1], [KRT17; KRT17; PC; K17; PC2; 39.1; CK-17; PCHC1; CK-17; K17]
Gene, Accession #[KRT17], Gene ID: 3872, NCBI: NP_000413, UniProt: Q04695
Catalog #MBS200354
Price$240, $315
Order / More InfoKRT17 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesKim S., et al. (2006) Nature. 441 (7091): 362-365; Troyanovsky S.M., et al. (1992) Eur J Cell Biol. 59 (1): 127-137; McGowan K.M. and Coulombe P.A. (1998) J Cell Biol. 143 (2): 469-486
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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