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Antigenic Specificity | Human Huntingtin-interacting protein 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Plays a role in clathrin-mediated endocytosis and trafficking. Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. Enhances androgen receptor (AR)-mediated transcription. May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. May play a functional role in the cell filament networks. May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors. |
Immunogen | Immunogen: Recombinant human Huntingtin-interacting protein 1 protein(410-690aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-20897 / sc-20899 / sc-33601 |
Other Names | [HIP-1; Huntingtin-interacting protein I; HIP-I], [HIP1; HIP1; SHON; HIP-I; ILWEQ; SHONbeta; SHONgamma; HIP-1; HIP-I] |
Gene, Accession # | [HIP1], Gene ID: 3092, NCBI: NP_001230127.1, UniProt: O00291 |
Catalog # | MBS1493805 |
Price | $120, $160 |
Order / More Info | Human Huntingtin-interacting protein 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |