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Antigenic Specificity | ADAM10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ADAM10 Antibody: Proinflammatory cytokine tumor necrosis factor-alpha (TNF-α) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-α, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-α, notch and its ligand delta. The genes encoding human, mouse, and bovine ADAM10 were recently cloned and d |
Immunogen | Immunogen: ADAM10 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human ADAM10. Buffer: ADAM10 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [ADAM10; RAK; kuz; AD10; AD18; MADM; CD156c; HsT18717; KUZ; Disintegrin and metalloproteinase domain-containing protein 10; CDw156; ADAM 10; ADAM metallopeptidase domain 10], [ADAM10; ADAM10; RAK; kuz; AD10; AD18; MADM; CD156c; HsT18717; KUZ; MADM; ADAM 10] |
Gene, Accession # | [ADAM10], Gene ID: 102, NCBI: NP_001101, UniProt: O14672 |
Catalog # | MBS150303 |
Price | $375 |
Order / More Info | ADAM10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |