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Antigenic Specificity | PEPT1 (Peptide transporter 1)- (N-terminal) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mg |
Concentration | 1ug/ul |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The PEPT1 (Peptide transporter 1) is Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. It may constitute a major route for the absorption of protein digestion end-products_recover. It belongs to the PTR2/POT transporter (TC 2.A.17)family. PEPT1 mediates oligopeptide-induced hormone secretion in enteroendocrine cells. PEPT1 transports muramyl dipeptide, activating NF-kappaB and stimulating IL-8 secretion in human colonic Caco2/bbe cells. The functionalities of PEPT1 and PEPT2 were largely conserved in terms of glycylsarcosine uptake kinetics and inhibitor specificity. Functional PepT1 recovers efficiently in a budded virus fraction and this expression system will be a useful tool for characterizat |
Immunogen | Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human PEPT1 (Peptide transporter 1) (Oligopeptide transporter, small intestine isoform (Peptide transporter 1) (Intestinal H (+)/peptide cotransporter) |
Other Names | [peptide transporter 1; Protein NRT1/ PTR FAMILY 8.1; peptide transporter 1; Peptide transporter PTR1], [PTR1; NPF8.1; ARABIDOPSIS THALIANA PEPTIDE TRANSPORTER 1; AtNPF8.1; ATPTR1; NPF8.1; NRT1/ PTR family 8.1; peptide transporter 1; PTR1; AtNPF8.1] |
Gene, Accession # | [PEPT1], Gene ID: 824581, NCBI: NP_190982.1 |
Catalog # | MBS418203 |
Price | $445 |
Order / More Info | PEPT1 (Peptide transporter 1)- (N-terminal) Antibody from MYBIOSOURCE INC. |
Product Specific References | Liang, R., et al, J. Biol. Chem. 270 (12), 6456-6463 (1995) Charrier, L., et al, Lab. Invest. 86 (5), 490-503 (2006) Saitoh, R., et al, Protein Expr. Purif. 46 (1), 130-135 (2006) Inoue, M., et al, Cancer Lett. 230 (1), 72-80 (2005) Matsumura, K., et al, Biochem. Biophys. Res. Commun. 336 (4), 1028-1032 (2005) Biegel, A., et al, J. Med. Chem. 48 (13), 4410-4419 (2005) Irie, M., et al, J. Physiol. (Lond.) 565 (PT 2), 429-439 (2005) Alteheld, B., et al, J. Nutr. 135 (1), 19-26 (2005) Vavricka, S.R., et al, Gastroenterology 127 (5), 1401-1409 (2004) Zhang, E.Y., et al, Mol. Pharm. 1 (3), 201-210 (2004) Herrera-Ruiz, D., et al, Mol. Pharm. 1 (2), 136-144 (2004) |