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Antigenic Specificity | CD14 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.1 mL |
Concentration | 1ug/ul |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP). LBP and CD14 antigen serves two physiological roles. These proteins act as opsonin and opsonic receptor, respectively, to promote the phagocytic uptake of bacteria or LPScoated particles by macrophages. |
Immunogen | Immunogen: Ni-NTA purified recombinant human CD14 expressed in E Coli strain BL21 (DE3). |
Other Names | [CD14; Monocyte differentiation antigen CD14; monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; CD_antigen: CD14], [CD14; CD14] |
Gene, Accession # | [CD14], Gene ID: 281048, NCBI: BAA21517.1 |
Catalog # | MBS418369 |
Price | $445 |
Order / More Info | CD14 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1.Richert MM, Schwertfeger KL, Ryder JW, Anderson SM: An atlas of mouse mammary gland development. J Mammary Gland Biol Neoplasia 2000,5 : 227-241. 2.Masso-Welch PA, Darcy KM, Stangle-Castor NC, Ip MM: A developmental atlas of rat mammary gland histology. J Mammary Gland Biol Neoplasia 2000,5 : 165-185. |