Phospho-beta-catenin (Ser33/37) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Phospho-beta-catenin (Ser33/37) antibody, protein, ELISA kits.
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| Antigenic Specificity | Phospho-beta-catenin (Ser33/37) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | humanpredicted: bovine, mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.05 mL, 0.2 mL |
| Concentration | 0.45 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Phospho-beta-catenin (Ser33/37) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 19-41 amino acids from human beta-catenin. Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion. Acts as a negative |
| Immunogen | n/a |
| Other Names | [Catenin beta-1; Beta-catenin; CTNNB1; CTNNB; Purified Rabbit (Pab)] |
| Gene, Accession # | [CTNNB1], Gene ID: 1499, NCBI: P35222.1, UniProt: P35222 |
| Catalog # | MBS9217366 |
| Price | $165, $370 |
| Order / More Info | Phospho-beta-catenin (Ser33/37) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Huelsken J.,et al.J. Cell Biol. 127:2061-2069(1994). Zhang C.,et al.Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). Muzny D.M.,et al.Nature 440:1194-1198(2006). Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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