LXR-A Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | LXR-A |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | LXR-A Antibody: LXR-A belongs to the Liver X Receptor family that encodes highly homologous transcription factors. Like the highly homologous LXR-B, LXR-A forms heterodimers with the retinoic acid receptor RXRalpha, function as sensors for cellular oxysterols which when activated, increase the expression of genes that control sterol and fatty acid metabolism and homeostasis. Recent experiments have indicated that the LXRs can also modulate both innate and adaptive immune responses. Human and mouse tumors produce LXR ligands that inhibit CCR7 expression on maturing dendritic cells (DCs), thereby allowing tumor immunoescape. In mouse models, it was shown that ablating LXR-A signaling led to an immune-mediated strong inhibition of tumor growth |
| Immunogen | Immunogen: LXR-A antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus human LXR-A. Buffer: LXR-A Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [LXR-A; LXRA; LXR-a; RLD-1; LXRA; Oxysterols receptor LXR-alpha; Liver X receptor alpha; nuclear receptor subfamily 1, group H, member 3], [NR1H3; NR1H3; LXRA; LXR-a; RLD-1; LXRA] |
| Gene, Accession # | [NR1H3], Gene ID: 10062, NCBI: NP_005684, UniProt: Q13133 |
| Catalog # | MBS150555 |
| Price | $375 |
| Order / More Info | LXR-A Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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