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Antigenic Specificity | IgM Chain C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: IgM Chain C Polyclonal Antibody detects endogenous levels of IgM Chain C. IgM antibodies play an important role in primary defense mechanisms. They have been shown to be involved in early recognition of external invaders like bacteria and viruses, cellular waste and modified self, as well as in recognition and elimination of precancerous and cancerous lesions. The membrane-bound form is found in the majority of normal B-cells alongside with IgD. Membrane-bound IgM induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. It may cause death of cells by apoptosis. It is also found in soluble form, which represents about 30% of the total serum immunoglobulins where it is found almost exclusively |
Immunogen | Immunogen: Synthesized peptide derived from IgM Chain C at AA range: 391-440 |
Other Names | [Rabbit IgM Chain C; Ig mu chain C region] |
Gene, Accession # | [IgM], NCBI: P01871.3, UniProt: P01871 |
Catalog # | MBS9708111 |
Price | $130, $220, $325 |
Order / More Info | IgM Chain C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |