Edit |   |
---|---|
Antigenic Specificity | ADAMTS4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total ADAMTS4 protein. This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human ADAMTS4. |
Other Names | [ADMP-1; ADAMTS-2; ADAMTS-4] |
Gene, Accession # | [ADAMTS4], Gene ID: 9507, NCBI: NP_005090.3, UniProt: O75173 |
Catalog # | MBS9410113 |
Price | $255 |
Order / More Info | ADAMTS4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |