SPPL2B (Center) Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | SPPL2B (Center) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.05 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This SPPL2B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 196-229 amino acids from the Central region of human SPPL2B. Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Functions in ITM2B and TNF processing. Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF- alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus. May play a role in the regulation of innate and adaptive immunity. |
| Immunogen | n/a |
| Other Names | [Purified Rabbit (Pab); Signal peptide peptidase-like 2B; SPP-like 2B; SPPL2b; 3423-; Intramembrane protease 4; IMP-4; Presenilin homologous protein 4; PSH4; Presenilin-like protein 1; SPPL2B; IMP4; KIAA1532; PSL1] |
| Gene, Accession # | [SPPL2B], Gene ID: 56928, NCBI: NP_001070706.1, UniProt: Q8TCT7 |
| Catalog # | MBS9215889 |
| Price | $165, $370 |
| Order / More Info | SPPL2B (Center) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Irmler M.,et al.Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases.Martoglio B.,et al.Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.Grigorenko A.P.,et al.Biochemistry (Mosc.) 67:826-834(2002).Nagase T.,et al.DNA Res. 7:143-150(2000).Grimwood J.,et al.Nature 428:529-535(2004). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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