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Antigenic Specificity | SYP |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, rat |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SYP antibody detects endogenous levels of total SYP. Description: Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore. Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases. Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex.Function: Possibly involved in structural functions as organizing other membrane compon |
Immunogen | Immunogen: Purified recombinant fragment of human SYP expressed in E. Coli Subcellular Location: Cytoplasmic Vesicle, Secretory Vesicle, Synaptic Vesicle Membrane. Cell Junction, Synapse, Synaptosome. Tissue Specificity: Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype. |
Other Names | [Major synaptic vesicle protein p38; MRX96; MRXSYP; Syn p38; Synaptophysin; Syp; SYPH; SYPH_HUMAN; SypI] |
Gene, Accession # | [SYP], Gene ID: 6855, NCBI: NP_003170.1, UniProt: P08247 |
Catalog # | MBS9602577 |
Price | $235, $295, $370 |
Order / More Info | SYP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |