TRIM35 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TRIM35 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: TRIM35 antibody detects endogenous levels of total TRIM35. Function: Reduces FGFR1-dependent tyrosine phosphorylation of PKM, inhibiting PKM-dependent lactate production, glucose metabolism, and cell growth (PubMed:25263439). Involved in the cell death mechanism (By similarity).Subunit Structure: Interacts with PKM isoform M2, but not isoform M1; this interaction may compete with that between PKM and FGFR1, and hence reduces FGFR1-dependent tyrosine phosphorylation of PKM.Similarity: The RING finger domain and the coiled-coil region are required for the apoptosis-inducing activity. Belongs to the TRIM/RBCC family. |
| Immunogen | Immunogen: A synthesized peptide derived from human TRIM35 Subcellular Location: Cytoplasm. Nucleus. Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies. Predicted Cross Reactivity: Rabbit, Dog Similarity: Rabbit (88%), Dog (88%) |
| Other Names | [0710005M05Rik; A430106H13Rik; AW046487; Hemopoietic lineage switch protein 5; HLS5; KIAA1098; Macrophage derived apoptosis inducing RBCC protein; MAIR; MGC17233; mKIAA1098; NC8; Protein MAIR; Protein Nc8; TRI35_HUMAN; TRIM35; Tripartite motif containing 35; Tripartite motif containing protein 35; Tripartite motif-containing protein 35] |
| Gene, Accession # | [TRIM35], Gene ID: 23087, NCBI: NP_741983.2, UniProt: Q9UPQ4 |
| Catalog # | MBS9609205 |
| Price | $240, $280 |
| Order / More Info | TRIM35 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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