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Antigenic Specificity | AGT (NT) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal Antibody to detect AGT in human samples. Background: Angiotensinogen, also known as AGT and SERPINA8, is a member of the serpin family. It is analpha-2-globulinthat is produced constitutively and released into the circulation mainly by the liver. Angiotensinogen is a essential component of the renin-angiotensin system (RAS) and a potent regulator of blood pressure. It is expressed by the liver and secreted in plasma. Angiotensinogen is cleaved into three chains: Angiotensin-1 (Ang I), Angiotensin-2 (Ang II), and Angiotensin-3 (Ang III). Angiotensin-1 is a substrate of ACE (angiotensin converting enzyme) that removes a dipeptide to yield the physiologically active peptide angiotensin-2. Angiotensin-1 and angiotensin-2 can be furth |
Immunogen | Immunogen: This AGT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human AGT. Positive Control: Western blot: HepG2 cell lysate, IHC: human hepatocarcinoma tissue |
Other Names | [AGT; SERPINA8; Angiotensinogen; Serpin A8; Angiotensin-1; Angiotensin I; Angiotensin-2; Angiotensin II; Angiotensin-3; Angiotensin III;], [AGT; AGT; ANHU; SERPINA8; SERPINA8; Ang I; Ang II; Ang III; Ang IV] |
Gene, Accession # | [AGT], Gene ID: 183, NCBI: NP_000020.1, UniProt: P01019 |
Catalog # | MBS840730 |
Price | $290 |
Order / More Info | AGT (NT) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |