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Antigenic Specificity | SWAP70 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2b |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous levels of SWAP70 and does not cross-react with related proteins. Phosphatidylinositol 3, 4, 5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3, 4)-bisphosphate production and cell protrusion |
Immunogen | Immunogen: Purified recombinant human SWAP70 protein fragments expressed in E Coli. Cellular Localization: Cytoplasm; Cell Membrane |
Other Names | [Switch-associated protein 70], [HSPC321; SWAP-70; FLJ39540; KIAA0640] |
Gene, Accession # | [SWAP70], Gene ID: 23075, NCBI: NP_001284643.1, UniProt: Q9UH65 |
Catalog # | MBS857782 |
Price | $300 |
Order / More Info | SWAP70 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |