RUFY1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RUFY1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: RUFY1 antibody detects endogenous levels of total RUFY1. Function: Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking.Subunit Structure: Interacts with BMX. May interact with SSB. Interacts with RAB4 and RAB5 that have been activated by GTP-binding.Post-translational Modifications: Phosphorylation on Tyr-389 and/or Tyr-400 is required for interaction with BMX and endosomal targeting.Similarity: The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate in membranes of early endosomes and penetrates bilayers. The FYVE domain insertion into PtdIns3P-enriched membranes is substantially increased in acidic conditions. |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasm. Early endosome membrane. Tissue Specificity: Broadly expressed, with highest levels in lung, testis, kidney and brain. Predicted Cross Reactivity: Pig, Rabbit, Dog, Chicken Similarity: Pig (100%), Rabbit (100%), Dog (89%), Chicken (80%) |
| Other Names | [3000002E04Rik; FLJ22251; FYVE finger protein EIP1; FYVE-finger protein EIP1; La binding protein 1; La-binding protein 1; OTTHUMP00000161521; Rab4 interacting protein; Rab4-interacting protein; RABIP4; RUFY1; RUFY1_HUMAN; RUN and FYVE domain containing 1; RUN and FYVE domain-containing protein 1; RUN and FYVE domains containing protein 1; ZFYVE12; Zinc finger FYVE domain containing protein 12; Zinc finger FYVE domain-containing protein 12] |
| Gene, Accession # | [RUFY1], Gene ID: 80230, NCBI: NP_001035541.1, UniProt: Q96T51 |
| Catalog # | MBS9605902 |
| Price | $240, $280 |
| Order / More Info | RUFY1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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