PACS2 (C-term), 642-671 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PACS2 (C-term), 642-671 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This PACS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 642-671 amino acids from the C-terminal region of human PACS2. Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments. |
| Immunogen | n/a |
| Other Names | [Phosphofurin acidic cluster sorting protein 2; PACS-2; PACS1-like protein; PACS2; KIAA0602; PACS1L] |
| Gene, Accession # | [PACS2], Gene ID: 23241, NCBI: NP_001094383.2, UniProt: Q86VP3 |
| Catalog # | MBS9208613 |
| Price | $165, $370 |
| Order / More Info | PACS2 (C-term), 642-671 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010) Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010) Aslan, J.E., et al. Mol. Cell 34(4):497-509(2009) Myhill, N., et al. Mol. Biol. Cell 19(7):2777-2788(2008) Atkins, K.M., et al. J. Biol. Chem. 283(17):11772-11784(2008) |
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MYBIOSOURCE INC.
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