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Antigenic Specificity | PAK6 (Ser-165), phospho-specific |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody was cross-adsorbed to unphosphorylated PAK6 (Ser-165) peptide then affinity purified using phospho-PAK6 (Ser-165) peptide. The antibody detects a 75 kDa* band on SDS-PAGE immunoblots of human PAK6 recombinant protein phosphorylated with ERK2. This reactivity is specifically blocked by pre-incubation with phospho-PAK6 (Ser-165) peptide and also by treatment with lambda phosphatase. p21-activated kinase 6 (PAK6) is a member of the PAK family of serine/threonine kinases. These kinases have a highly conserved amino-terminal Cdc42/Rac interactive binding domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and th |
Immunogen | Immunogen: PAK6 (Ser-165) synthetic peptide (coupled to carrier protein) corresponding to amino acids around serine 165 in human PAK6. The sequence used has two amino acid differences compared to rat and mouse PAK6. |
Other Names | [PAK6 (Ser-165); phospho-specific; p21 activated kinase 6], [PAK6; PAK6; PAK5; PAK5] |
Gene, Accession # | Gene ID: 56924, NCBI: NP_001122101.1, UniProt: Q9NQU5 |
Catalog # | MBS472045 |
Price | $385 |
Order / More Info | PAK6 (Ser-165), phospho-specific Antibody from MYBIOSOURCE INC. |
Product Specific References | • Kaur, R. et al. (2005) J. Biol. Chem. 280(5) :3323.• Schrantz, N. et al. (2004) J. Biol. Chem. 279(3):1922.• Lee, S.R. et al. (2002) Mol. Endocrin. 16(1):85. |