Phospho-ANXA2 (Tyr238) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-ANXA2 (Tyr238)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, ratpredicted: porcine, bovine, horse, sheep, rabbit, dog, chicken, Xenopus
Isotypen/a
Formatpeptide affinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA)
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DescriptionSpecificity: Phospho-ANXA2 (Tyr238) Antibody detects endogenous levels of ANXA2 only when phosphorylated at Tyr238. Description: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9 (PubMed:18799458, PubMed:24808179, PubMed:22848640).Post Translational Modifications: Phosphorylation of Tyr-24 enhances heat stress-induced translocation to the cell surface. ISGylated.Subunit Structure: Heterotetramer containing 2 light ch
ImmunogenImmunogen: A synthesized peptide derived from human ANXA2 around the phosphorylation site of Tyr238.
Other Names[Annexin A2; Annexin II; Annexin II, heavy chain; Annexin-2; ANX 2; ANX2; ANX2L4; ANXA2; ANXA2_HUMAN; arylsulfatase B; CAL1H; Calpactin I heavy chain; calpactin I heavy polypeptide (p36); Calpactin I heavy polypeptide; Calpactin-1 heavy chain; chromobindin 8; Chromobindin-8; Epididymis secretory protein Li 270; HEL S 270; LIP2; Lipocortin II; LPC2; LPC2D; p36; P36 protein; PAP-IV; Placental anticoagulant protein IV; Protein I]
Gene, Accession #[ANXA2], Gene ID: 302, NCBI: NP_001002857.1, UniProt: P07355
Catalog #MBS9610459
Price$225, $280, $340
Order / More InfoPhospho-ANXA2 (Tyr238) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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