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Antigenic Specificity | Phospho-ANXA2 (Tyr238) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, bovine, horse, sheep, rabbit, dog, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-ANXA2 (Tyr238) Antibody detects endogenous levels of ANXA2 only when phosphorylated at Tyr238. Description: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9 (PubMed:18799458, PubMed:24808179, PubMed:22848640).Post Translational Modifications: Phosphorylation of Tyr-24 enhances heat stress-induced translocation to the cell surface. ISGylated.Subunit Structure: Heterotetramer containing 2 light ch |
Immunogen | Immunogen: A synthesized peptide derived from human ANXA2 around the phosphorylation site of Tyr238. |
Other Names | [Annexin A2; Annexin II; Annexin II, heavy chain; Annexin-2; ANX 2; ANX2; ANX2L4; ANXA2; ANXA2_HUMAN; arylsulfatase B; CAL1H; Calpactin I heavy chain; calpactin I heavy polypeptide (p36); Calpactin I heavy polypeptide; Calpactin-1 heavy chain; chromobindin 8; Chromobindin-8; Epididymis secretory protein Li 270; HEL S 270; LIP2; Lipocortin II; LPC2; LPC2D; p36; P36 protein; PAP-IV; Placental anticoagulant protein IV; Protein I] |
Gene, Accession # | [ANXA2], Gene ID: 302, NCBI: NP_001002857.1, UniProt: P07355 |
Catalog # | MBS9610459 |
Price | $225, $280, $340 |
Order / More Info | Phospho-ANXA2 (Tyr238) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |