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Antigenic Specificity | AQP4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Aquaporin 4 is found in the basolateral cell membrane of principal collecting duct cells and provide a pathway for water to exit these cells. The gene of AQP4 is mapped to 18q11.2-q12.1. Similar to other aquaporins, the AQP4 gene is composed of 4 exons encoding 127, 55, 27, and 92 amino acids separated by introns of 0.8, 0.3, and 5.2 kb. Unlike other aquaporins, an alternative coding initiation sequence (designated exon 0) was located 2.7 kb upstream of exon 1. When spliced together, M1 and the subsequent 10 amino acids are encoded by exon 0; the next 11 amino acids and M23 are encoded by exon 1. AQP4 is expressed in astrocytes and is upregulated by direct insult to the central nervous system.3 AQP4 is the predominant water channel in the b |
Immunogen | Immunogen: AQP4 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human AQP4, identical to the related rat and Rabbit sequence as the immunogen |
Other Names | [Affinity Purified Rabbit AQP4; AQP4; AQP4; AQP 4; AQP 4; AQP-4; AQP-4; AQP4; Aquaporin 4] |
Gene, Accession # | [AQP4] |
Catalog # | MBS5312620 |
Price | $345 |
Order / More Info | AQP4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |