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Antigenic Specificity | TNFSF18/Gitrl Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Tumor necrosis factor ligand superfamily member 18, also known as AITRL or GITRL, is a protein that in humans is encoded by the TNFSF18 gene. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor(TNF) ligand family. It is mapped to 1q25.1. TNFSF18 is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. TNFSF18-dependent modulation of tryptophan catabolism may represent an important mechanism of action of glucocorticoids, both physiologically and therapeutically.Protein Fu |
Immunogen | Immunogen: E Coli-derived human TNFSF18 recombinant protein (Position: F70-S199). Subcellular Localization: Cell membrane Tissue Specificity: Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. |
Other Names | [Tumor necrosis factor ligand superfamily member 18; Activation-inducible TNF-related ligand; AITRL; Glucocorticoid-induced TNF-related ligand; hGITRL; TNFSF18; AITRL; GITRL; TL6; UNQ149/PRO175] |
Gene, Accession # | [TNFSF18], Gene ID: 8995, NCBI: NP_005083.2, UniProt: Q9UNG2 |
Catalog # | MBS1750870 |
Price | $315 |
Order / More Info | TNFSF18/Gitrl Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |