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Antigenic Specificity | FKBP1A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total FKBP1A protein. The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human FKBP1A. |
Other Names | [FKBP1; PKC12; PKCI2; FKBP12; PPIASE] |
Gene, Accession # | [FKBP1A], Gene ID: 2280, NCBI: NP_000792.1, UniProt: P62942 |
Catalog # | MBS9404059 |
Price | $255 |
Order / More Info | FKBP1A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |