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Antigenic Specificity | HP1 gamma |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human; mouse; rat |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemmistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HP1 gamma mouse monoclonal antibody detects endogenous levels of HP1 gamma. Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the recruitment of the methyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box eleme |
Immunogen | Immunogen: A synthetic peptide Fragment: Fab fragment |
Other Names | [HP1 gamma; CBX 3,CBX3;Chromobox homolog 3;Heterochromatin like protein 1;] |
Gene, Accession # | [HP1 gamma], Gene ID: 11335, NCBI: NP_009207.2, UniProt: Q13185 |
Catalog # | MBS9611255 |
Price | $235, $295, $370 |
Order / More Info | HP1 gamma Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |