RGL4 (N-term), 98-125 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRGL4 (N-term), 98-125
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis RGL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-125 amino acids from the N-terminal region of human RGL4. Ral GDS (Ral guanine nucleotide dissociation stimulator) is a guanine nucleotide exchange factor (GEF) that activates Ral and is implicated in oncogenic Ras-induced cell transformation. RGL4 (ral guanine nucleotide dissociation stimulator-like 4), also known as Rgr, is a 473 amino acid protein that localizes to the cytoplasmic vesicle of cells. Belonging to the GEF family of proteins, RGL4 induces phosphorylation of ERKs, p38 and JNK kinases, and it increases the levels of GTP bound forms of Ral and Ras. Ras activation is crucial for the transforming activity of RGL4. Due to its
Immunogenn/a
Other Names[Ral-GDS-related protein; hRGR; Ral guanine nucleotide dissociation stimulator-like 4; RalGDS-like 4; RGL4; RGR]
Gene, Accession #[RGL4], Gene ID: 266747, NCBI: NP_705843.1, UniProt: Q8IZJ4
Catalog #MBS9205570
Price$165, $370
Order / More InfoRGL4 (N-term), 98-125 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesHernandez-Munoz, I., et al. Cancer Res. 63(14):4188-4195(2003) Hernandez-Munoz, I., et al. Oncogene 19(23):2745-2757(2000) Dunham, I., et al. Nature 402(6761):489-495(1999) D'Adamo, D.R., et al. Oncogene 14(11):1295-1305(1997)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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