CD79a (IGBP1) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD79a (IGBP1)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
FormatProtein G purified
Size0.1 mg, 0.2 mg
Concentrationn/a
ApplicationsWestern Blot (WB), IHC (Immunohistochemistry), ELISA (EIA)
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DescriptionCD79 is a dimeric transmembrane protein that is associated with membrane immunoglobulin and initiates B-cell signaling following engagement of the latter by antigen.1-3 The 2 component chains of CD79, referred to as CD79a and CD79b. CD79a as well as CD79b is purported to be a B cell-specific antigen. CD79a expression begins at the earliest pro-B stage of development and continues throughout Bcell differentiation to the plasma cell stage,6 making it one of the most useful pan-B-cell markers used in routine immunophenotypic analysis. In addition, CD79a expression seems to be restricted to B-lineage cells (ie,a diagnostically specific B-cell marker).
ImmunogenSource Note: Polyclonal CD79a antibody was produced from sera of rabbits immunized with synthetic protein containing CD79a antigenic determinants.
Other Names[Rabbit Human CD79 purified; IGBP-1; IGBP1; cd79; cd-79;; PAb], [CD79A; IGA; MB1]
Gene, Accession #[CD79], Gene ID: 973, NCBI: NP_001774.1, UniProt: P11912
Catalog #MBS551050
Price$280, $385
Order / More InfoCD79a (IGBP1) Antibody from MYBIOSOURCE INC.
Product Specific References• b cell depletion with anti-CD79 mabs ameliorates autoimmune disease in mrl/lpr mice.J. Immunol., Sep 2008; 181: 2961 - 2972. • antibody-drug conjugates targeted to CD79 for the treatment of non-hodgkin lymphoma.Blood, Jul 2007; 110: 616 - 623. • antibody-drug conjugates targeted to CD79 for the treatment of non-hodgkins lymphoma.Blood (ASH Annual Meeting Abstracts), Nov 2006; 108: 2524. • CD79 alpha/CD79 beta heterodimers are expressed on pro-b cell surfaces without associated mu heavy chain.Int. Immunol., Nov 1997; 9: 1767 - 1772.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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