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Antigenic Specificity | GABAA Receptor, gamma2-Subunit |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | serum |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Specific for the ~46k gamma2-subunit of the GABAA receptor in Western blots of rat brain extracts. Rabbit polyclonal antibody |
Immunogen | Antigen: Peptide representing a sequence that is specific for the gamma2-subunit of rat GABAA receptor. The sequence of the immunogen has no homology with any other GABAA R-subunit. Immunogen Information: Synthetic peptide corresponding to amino acid residues specific to the gamma 2 subunit conjugated to KLH. Immunogen Species: Rat |
Other Names | [gamma-aminobutyric acid receptor subunit gamma-2; Gamma-aminobutyric acid receptor subunit gamma-2; gamma-aminobutyric acid receptor subunit gamma-2; GABA(A) receptor subunit gamma-2; gamma-aminobutyric acid A receptor, gamma 2; gamma-aminobutyric acid A receptor, gamma 2; gamma-aminobutyric acid (GABA-A) receptor, subunit gamma 2; gamma-aminobutyric acid (GABA) A receptor, gamma 2; GABA(A) receptor subunit gamma-2], [Gabrg2; Gabrg2] |
Gene, Accession # | [GABRG2], Gene ID: 29709, NCBI: NP_899156.1, UniProt: P18508 |
Catalog # | MBS502054 |
Price | $360 |
Order / More Info | GABAA Receptor, gamma2-Subunit Antibody from MYBIOSOURCE INC. |
Product Specific References | • Brandon NJ, Jovanovic JN, Colledge M, Kittler JT, Brandon JM, Scott JD, Moss SJ (2003) A kinase anchoring protein 79/150 facilitates the phosphorylation of GABAA receptors by cAMP-dependent protein kinase via selective interaction with receptor beta-subunits. Mol Cell Neurosci 22:87-97• McKernan RM, et al. (2000) Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABAA receptor alpha1-subtype. Nature Neurosci 3:587-592.• Mehta AK, Ticku MK (1998) Prevalence of the GABAA receptor assemblies containing alpha1-subunit in the rat cerebellum and cerebral cortex as determined by immunoprecipitation: Lack of modulation by chronic ethanol administration. Mol Brain Res 67:194-199.• Ogris W, Poltl A, Hauer B, Ernst M, Oberto A, Wulff P, Hoger H, Wisden W, Sieghart W (2004) Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABAA receptor gamma2-subunit. Biochem Pharmacol 68:1621-1629.• Olsen RW, Tobin AJ (1990) Molecular biology of GABAA receptors. FASEB 4:1469-1480. |