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Antigenic Specificity | Mannose 6 Phosphate Receptor, Cation-independent |
Clone | [10K74] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2B |
Format | Protein G purified |
Size | 0.5 mg |
Concentration | ~0.5mg/ml (after reconstitution) |
Applications | ELISA (EL/EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human IGF-II R. Insulin-like Growth Factor 2 receptor (IGF-II R), also known as cation-independent mannose-6 phosphate receptor (CI-MPR), is a 300kD, 2264aa type I transmembrane glycoprotein of the P-type lectin family. The extracellular region contains 15 repeats that mediate homodimer formation and multifunctional binding of IGF-II and many other proteins that do and do not contain mannose-6 phosphates. IGF-II R generally regulates endocytosis and lysosomal/endosomal trafficking. Human IGF-II R shares 85% aa identity with mouse and cow IGF-II R within the extracellular region used as an immunogen. |
Immunogen | Immunogen: Recombinant protein corresponding to ser1510-Phe2108 of human IGF-II R, expressed in NSO cells. Species Sequence Homology: mouse and bocine 85%. |
Other Names | Mannose 6 Phosphate Receptor, Cation-independent (Cation-independent Mannose-6-phosphate Receptor, CI Man-6-P Receptor, CI-MPR, M6PR, 300kD Mannose 6-phosphate Receptor, MPR 300, Insulin-like Growth Factor 2 Receptor, Insulin-like Growth Factor II Recepto |
Gene, Accession # | Gene ID: 3482, UniProt: P11717 |
Catalog # | MBS632483 |
Price | $810 |
Order / More Info | Mannose 6 Phosphate Receptor, Cation-independent Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |