Mannose 6 Phosphate Receptor, Cation-independent Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMannose 6 Phosphate Receptor, Cation-independent
Clone[10K74]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2B
FormatProtein G purified
Size0.5 mg
Concentration~0.5mg/ml (after reconstitution)
ApplicationsELISA (EL/EIA)
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DescriptionRecognizes human IGF-II R. Insulin-like Growth Factor 2 receptor (IGF-II R), also known as cation-independent mannose-6 phosphate receptor (CI-MPR), is a 300kD, 2264aa type I transmembrane glycoprotein of the P-type lectin family. The extracellular region contains 15 repeats that mediate homodimer formation and multifunctional binding of IGF-II and many other proteins that do and do not contain mannose-6 phosphates. IGF-II R generally regulates endocytosis and lysosomal/endosomal trafficking. Human IGF-II R shares 85% aa identity with mouse and cow IGF-II R within the extracellular region used as an immunogen.
ImmunogenImmunogen: Recombinant protein corresponding to ser1510-Phe2108 of human IGF-II R, expressed in NSO cells. Species Sequence Homology: mouse and bocine 85%.
Other NamesMannose 6 Phosphate Receptor, Cation-independent (Cation-independent Mannose-6-phosphate Receptor, CI Man-6-P Receptor, CI-MPR, M6PR, 300kD Mannose 6-phosphate Receptor, MPR 300, Insulin-like Growth Factor 2 Receptor, Insulin-like Growth Factor II Recepto
Gene, Accession #Gene ID: 3482, UniProt: P11717
Catalog #MBS632483
Price$810
Order / More InfoMannose 6 Phosphate Receptor, Cation-independent Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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