MADD Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMADD
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
FormatDEAE purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionMADD Antibody: MAP kinase-activating death domain protein (MADD) was initially identified as the type 1 tumor necrosis factor receptor (TNFR1) associated protein though their death domains. Overexpression of MADD activates MAP kinases ERK and JNK and induces the phosphorylation of cytosolic phospholipase A2. MADD shares 98% identity with DENN (for differentially expressed in neoplastic vs. normal cells), which was recently identified as a substrate for c-jun N-terminal kinase 3 (JNK3). MADD has greater than 94% overall identity to a GDP/GTP exchange protein Rab3-GEP. MADD is 87% identical to KIAA0358, a brain protein of unknown function. Identification of MADD as a component of the TNFR1 signaling complex and the similarity between MADD and
ImmunogenImmunogen: MADD antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human MADD. Buffer: MADD Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[MADD; DENN; IG20; RAB3GEP; DENN; KIAA0358; MAP kinase-activating death domain protein; Differentially expressed in normal and neoplastic cells; MAP-kinase activating death domain], [MADD; MADD; DENN; IG20; RAB3GEP]
Gene, Accession #[MADD], Gene ID: 8567, NCBI: AAD12154, UniProt: Q8WXG6
Catalog #MBS150188
Price$375
Order / More InfoMADD Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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