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Antigenic Specificity | MADD |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | DEAE purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MADD Antibody: MAP kinase-activating death domain protein (MADD) was initially identified as the type 1 tumor necrosis factor receptor (TNFR1) associated protein though their death domains. Overexpression of MADD activates MAP kinases ERK and JNK and induces the phosphorylation of cytosolic phospholipase A2. MADD shares 98% identity with DENN (for differentially expressed in neoplastic vs. normal cells), which was recently identified as a substrate for c-jun N-terminal kinase 3 (JNK3). MADD has greater than 94% overall identity to a GDP/GTP exchange protein Rab3-GEP. MADD is 87% identical to KIAA0358, a brain protein of unknown function. Identification of MADD as a component of the TNFR1 signaling complex and the similarity between MADD and |
Immunogen | Immunogen: MADD antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human MADD. Buffer: MADD Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [MADD; DENN; IG20; RAB3GEP; DENN; KIAA0358; MAP kinase-activating death domain protein; Differentially expressed in normal and neoplastic cells; MAP-kinase activating death domain], [MADD; MADD; DENN; IG20; RAB3GEP] |
Gene, Accession # | [MADD], Gene ID: 8567, NCBI: AAD12154, UniProt: Q8WXG6 |
Catalog # | MBS150188 |
Price | $375 |
Order / More Info | MADD Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |