Mouse GITRL Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse GITRL
Clone[YGL386]
Host SpeciesRat
Reactive Speciesn/a
IsotypeIgG1
Formatunconjugated
Size0.1 mg
ConcentrationIgG concentration 1.0 mg/ml
ApplicationsELISA (EIA), Flow cytometry (FC/FACS)
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DescriptionRat anti Mouse GITRL antibody, clone YGL386 recognizes mouse glucocorticoid-induced tumour necrosis factor receptor ligand (GITRL), a 20 kD member of the tumour necrosis factor ligand superfamily, otherwise known as TNSF18. Mouse GITRL is predominantly expressed on immature and mature dendritic cells, macrophages and B cells. Expression of mouse GITRL can be transiently up regulated on these cells, following lipolysaccharide (LPS) stimulation, but protein expression is rapidly down modulated shortly after stimulation. Studies demonstrate that GITRL can neutralise the suppressive effects of CD4+CD25+ regulatory T cells and can also provide a co-stimulatory signal for both na?ve and primed T cells, suggesting a key role for GITRL in the regul
Immunogenn/a
Other Names[tumor necrosis factor ligand superfamily member 18; Tumor necrosis factor ligand superfamily member 18; tumor necrosis factor ligand superfamily member 18; AITR ligand; GITR ligand; activation-inducible TNF-related ligand; glucocorticoid-induced TNF-related ligand; glucocorticoid-induced TNFR-related protein ligand; tumor necrosis factor (ligand) superfamily, member 18; Activation-inducible TNF-related ligand; AITRL; Glucocorticoid-induced TNF-related ligand; hGITRL], [TNFSF18; TNFSF18; TL6; AITRL; GITRL; hGITRL; AITRL; GITRL; TL6; AITRL; hGITRL]
Gene, Accession #[GITRL], Gene ID: 8995, NCBI: NP_005083.2, UniProt: Q9UNG2
Catalog #MBS212792
Price$300
Order / More InfoMouse GITRL Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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