LARGE (Center) Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | LARGE (Center) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.05 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine- beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1) (PubMed:22223806). Phosphorylated O- mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity and plays a key role in skeletal muscle function and regeneration. LARGE elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure initiated by B3GNT1/B4GAT1 by adding repeat |
| Immunogen | n/a |
| Other Names | [Purified Rabbit (Pab); Glycosyltransferase-like protein LARGE1; 2.4.-.-; Acetylglucosaminyltransferase-like 1A; Xylosyltransferase LARGE; 2.4.2.-; Beta-1,3-glucuronyltransferase LARGE; 2.4.1.-; LARGE; KIAA0609; LARGE1] |
| Gene, Accession # | [LARGE], Gene ID: 9215, NCBI: NP_004728.1, UniProt: O95461 |
| Catalog # | MBS9216888 |
| Price | $150 |
| Order / More Info | LARGE (Center) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Peyrard M.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:598-603(1999). Nagase T.,et al.DNA Res. 5:31-39(1998). Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004). Dunham I.,et al.Nature 402:489-495(1999). Fujimura K.,et al.Biochem. Biophys. Res. Commun. 329:1162-1171(2005). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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