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Antigenic Specificity | PRKAG3 (Center), 148-178 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PRKAG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-178 amino acids from the Central region of human PRKAG3. PRKAG3 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulato |
Immunogen | n/a |
Other Names | [5'-AMP-activated protein kinase subunit gamma-3; AMPK gamma3; AMPK subunit gamma-3; PRKAG3; AMPKG3] |
Gene, Accession # | [PRKAG3], Gene ID: 53632, NCBI: NP_059127.2, UniProt: Q9UGI9 |
Catalog # | MBS9201738 |
Price | $165, $370 |
Order / More Info | PRKAG3 (Center), 148-178 Antibody from MYBIOSOURCE INC. |
Product Specific References | Milan, D., et al., Science 288(5469):1248-1251 (2000). Cheung, P.C., et al., Biochem. J. 346 Pt 3, 659-669 (2000). |