BiP/GRP78 (C-term) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | BiP/GRP78 (C-term) |
| Clone | [9E4-2A7-H6] |
| Host Species | Mouse |
| Reactive Species | human, rat |
| Isotype | IgG1 |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | 0.8mg/ml |
| Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Entrez Summary: The 78 kDa glucose regulated protein/BiP (GRP78) belongs to the family of ~70 kDa heat shock proteins (HSP 70). GRP78 is a resident protein of the endoplasmic reticulum (ER) and may associate transiently with a variety of newly synthesized secretory and membrane proteins or permanently with mutant or defective proteins that are incorrectly folded, thus preventing their export from the ER lumen. GRP78 is a highly conserved protein that is essential for cell viability. The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the C terminus of GRP78 and other resident ER proteins including glucose regulated protein 94 (GRP 94) and protein disulfide isomerase (PDI). The presence of carboxy terminal KDEL appears to be n |
| Immunogen | Immunogen: Purified recombinant human BiP/GRP78 (C-terminus) protein fragments expressed in E Coli. Sensitivity: This antibody detects endogenous levels of BiP/GRP78 (C-terminus) and does not cross-react with related proteins. Sequence Similarities: Belongs to the heat shock protein 70 family |
| Other Names | [78 kDa glucose regulated protein; 78 kDa glucose-regulated protein; AL022860; AU019543; BIP; D2Wsu141e; D2Wsu17e; Endoplasmic reticulum lumenal Ca (2)-binding protein grp78; Endoplasmic reticulum lumenal Ca2 binding protein grp78; FLJ26106; Glucose Regulated Protein 78kDa; GRP 78; GRP-78; GRP78; GRP78_HUMAN; Heat shock 70 kDa protein 5; Heat Shock 70kDa Protein 5; Hsce70; HSPA 5; HSPA5; Immunoglobulin Heavy Chain Binding Protein; Immunoglobulin heavy chain-binding protein; mBiP; MIF2; Sez7], [hspa5; BIP; MIF2; GRP78] |
| Gene, Accession # | [BiP/GRP78], Gene ID: 3309, NCBI: NP_005338.1, UniProt: P11021 |
| Catalog # | MBS475111 |
| Price | $335 |
| Order / More Info | BiP/GRP78 (C-term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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