Gai2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Gai2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.03 mg, 0.1 mg |
| Concentration | 0.5 mg/ml |
| Applications | Western Blot (WB), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background: Galphai2 is a 40-41 kDa alpha-subunit of heterotrimeric protein that shares sequence homology with Galphai3 and Galphai1. All these G proteins can be ADP-ribosylated at the carboxy terminal Cys of the CAAX sequence, interfering with receptor coupling. Galphai2 is expressed widely in tissues and cell lines. Activation of PLC-beta by Galphai-coupled receptors is the result of release of Gbetag subunits from Galphai. Galphai2 regulates potassium channel activation. Mutation at Arg179 has been identified in tumors. This and the Q205L mutant inhibit adenylyl cyclase. |
| Immunogen | Immunogen: Synthetic peptide surrounding amino acid 229 of human Gai2 |
| Other Names | [guanine nucleotide binding protein G; GNAI2B; guanine nucleotide binding protein], [GNAI2; GNAI2; GIP; GNAI2B; H_LUCA15.1; H_LUCA16.1; GNAI2B] |
| Gene, Accession # | [Gai2], Gene ID: 2771, NCBI: AAM12620 |
| Catalog # | MBS840740 |
| Price | $150, $290 |
| Order / More Info | Gai2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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