PGRMC1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPGRMC1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: PGRMC1 antibody detects endogenous levels of total PGRMC1. Description: This gene encodes a putative membrane-associated progesterone steroid receptor. The protein is expressed predominantly in the liver and kidney.Function: Component of a progesterone-binding protein complex (PubMed:28396637). Binds progesterone (PubMed:25675345). Has many reported cellular functions (heme homeostasis, interaction with CYPs).Subunit Structure: Homodimer. Forms stable homodimer through hydrophobic heme-heme stacking interactions.Similarity: The cytochrome b5 heme-binding domain lacks the conserved iron-binding His residues at positions 107 and 131. Belongs to the cytochrome b5 family. MAPR subfamily.
ImmunogenImmunogen: A synthesized peptide derived from human PGRMC1 Subcellular Location: Microsome membrane. Endoplasmic Reticulum Membrane. Tissue Specificity: Widely expressed, with highest expression in liver and kidney. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit Similarity: Pig (100%), Bovine (89%), Horse (89%), Sheep (89%), Rabbit (89%)
Other Names[HPR6.6; Membrane associated progesterone receptor component 1; Membrane-associated progesterone receptor component 1; mPR; PGRC1_HUMAN; PGRMC; Pgrmc1; Progesterone binding protein; Progesterone receptor membrane component 1]
Gene, Accession #[PGRMC1], Gene ID: 10857, NCBI: NP_001269550.1, UniProt: O00264
Catalog #MBS9608059
Price$240, $280
Order / More InfoPGRMC1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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