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Antigenic Specificity | PGRMC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PGRMC1 antibody detects endogenous levels of total PGRMC1. Description: This gene encodes a putative membrane-associated progesterone steroid receptor. The protein is expressed predominantly in the liver and kidney.Function: Component of a progesterone-binding protein complex (PubMed:28396637). Binds progesterone (PubMed:25675345). Has many reported cellular functions (heme homeostasis, interaction with CYPs).Subunit Structure: Homodimer. Forms stable homodimer through hydrophobic heme-heme stacking interactions.Similarity: The cytochrome b5 heme-binding domain lacks the conserved iron-binding His residues at positions 107 and 131. Belongs to the cytochrome b5 family. MAPR subfamily. |
Immunogen | Immunogen: A synthesized peptide derived from human PGRMC1 Subcellular Location: Microsome membrane. Endoplasmic Reticulum Membrane. Tissue Specificity: Widely expressed, with highest expression in liver and kidney. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit Similarity: Pig (100%), Bovine (89%), Horse (89%), Sheep (89%), Rabbit (89%) |
Other Names | [HPR6.6; Membrane associated progesterone receptor component 1; Membrane-associated progesterone receptor component 1; mPR; PGRC1_HUMAN; PGRMC; Pgrmc1; Progesterone binding protein; Progesterone receptor membrane component 1] |
Gene, Accession # | [PGRMC1], Gene ID: 10857, NCBI: NP_001269550.1, UniProt: O00264 |
Catalog # | MBS9608059 |
Price | $240, $280 |
Order / More Info | PGRMC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |