HPSE Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHPSE
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein G purified
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionEndoglycosidase that cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Participates in extracellular matrix (ECM) degradation and remodeling. Selectively cleaves the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying either a 3-O-sulfo or a 6-O-sulfo group. Can also cleave the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying a 2-O-sulfo group, but not linkages between a glucuronic acid unit and a 2-O-sulfated iduronic acid moiety. It is essentially inactive at neutral pH but becomes active under acidic conditions such as during tumor invasion and in inflammatory processes. Facilitates cell migration associated with metastasis, wo
ImmunogenImmunogen: Recombinant Human Heparanase protein (263-523AA)
Other Names[Heparanase; Endo-glucoronidase; Heparanase-1; Hpa1; Heparanase 8 kDa subunit; Heparanase 50 k; HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1]
Gene, Accession #[HPSE], Gene ID: 10855, NCBI: NP_001092010.1, UniProt: Q9Y251
Catalog #MBS7048381
Price$160, $235
Order / More InfoHPSE Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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